James Harden of the Philadelphia 76ers

With an impressive 18-10 record against Eastern Conference opponents and one of the NBA's best defenses, the Philadelphia 76ers have a strong advantage when taking on the Orlando Magic.

The Philadelphia 76ers have been a formidable force in the Eastern Conference this season, standing at 32-16 and second in the conference. In their last matchup, the 76ers defeated the Denver Nuggets 126-119, with Joel Embiid scoring an impressive 47 points. This victory highlights the team's impressive offensive capabilities, which they will look to employ against the Magic.

Philadelphia also boasts one of the best defenses in the NBA, allowing only 104.5 points per game and holding opponents to a 47.4% shooting rate. The 76ers' combination of strong offense and defense make them one of the toughest teams in the Eastern Conference.

The Orlando Magic have had a more challenging season, with a record of 19-31 and 13th in the Eastern Conference. While the Magic have had some impressive performances, they have not been able to consistently string together wins. The Magic will need to bring their best effort if they hope to defeat the 76ers.

Taking into account the matchup between the Philadelphia 76ers and the Orlando Magic, the 76ers are the clear favorite. The 76ers have a better record and have been able to beat some of the top teams in the conference. With their strong offensive and defensive production, the 76ers are well-suited to maintain their success and defeat the Magic.